ABSTRACT
Nephropathy in type 2 diabetes has emerged as a severe clinical problem in diabetes of this type and is now much more frequently seen than advanced renal disease in type 1 diabetes (1,2). However, in the 1970s and 1980s, renal complications due to type 2 diabetes seemed to be rare in the clinic so this new development is surprising. Today, most patients in dialysis units are type 2 diabetics, which raises the following question: Why and how did type 2 diabetes lose its “renal innocence” (3-5)?
