ABSTRACT
INTRODUCTION Azole antifungal drugs are the most widely employed antifungal agents in clinical practice. When first introduced in the late 1970s, these agents greatly changed the way fungal infections were managed by introducing choice for clinicians as well as oral therapy options for treating systemic fungal diseases. Today, their clinical utility spans every aspect of treating fungal infection from topical therapy for superficial diseases to intravenous preparations for the most severe, life-threatening invasive mycoses.
