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Bacterial Resistance to Antimicrobials
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Bacterial Resistance to Antimicrobials

Bacterial Resistance to Antimicrobials

Edited ByRichard G. Wax, Kim Lewis, Abigail A. Salyers, Harry Taber
Edition 2nd Edition
First Published 2007
eBook Published 5 December 2007
Pub. location Boca Raton
Imprint CRC Press
DOIhttps://doi.org/10.1201/9781420008753
Pages 448 pages
eBook ISBN 9781420008753
SubjectsBioscience, Medicine, Dentistry, Nursing & Allied Health
Get Citation

Get Citation

Wax, R. (Ed.), Lewis, K. (Ed.), Salyers, A. (Ed.), Taber, H. (Ed.). (2008). Bacterial Resistance to Antimicrobials. Boca Raton: CRC Press, https://doi.org/10.1201/9781420008753
ABOUT THIS BOOK

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Unde

TABLE OF CONTENTS
chapter 1|10 pages
Microbial Drug Resistance: A Historical Perspective
View abstract
chapter 2|12 pages
Ecology of Antibiotic Resistance Genes
View abstract
chapter 3|22 pages
Global Response Systems That Confer Resistance
View abstract
chapter 4|26 pages
Multidrug Effl ux Pumps: Structure, Mechanism, and Inhibition
View abstract
chapter 5|32 pages
Mechanisms of Aminoglycoside Antibiotic Resistance
View abstract
chapter 6|30 pages
Resistance to β-Lactam Antibiotics Mediated by β-Lactamases: Structure, Mechanism, and Evolution
View abstract
chapter 7|36 pages
Target Modifi cation as a Mechanism of Antimicrobial Resistance
View abstract
chapter 8|14 pages
Antibiotic Permeability
View abstract
chapter 9|46 pages
Genetic Methods for Detecting Bacterial Resistance Genes
View abstract
chapter 10|26 pages
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
View abstract
chapter 11|36 pages
Antimicrobial Resistance in the Enterococcus
View abstract
chapter 12|22 pages
Methicillin Resistance in Staphylococcus aureus
View abstract
chapter 13|30 pages
Mechanism of Drug Resistance in Mycobacterium tuberculosis
View abstract
chapter 14|20 pages
Antibiotic Resistance in Enterobacteria
View abstract
chapter 15|14 pages
Resistance as a Worldwide Problem
View abstract
chapter 16|32 pages
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
View abstract
chapter 17|10 pages
Antibacterial Drug Discovery in the 21st Century
View abstract

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Unde

TABLE OF CONTENTS
chapter 1|10 pages
Microbial Drug Resistance: A Historical Perspective
View abstract
chapter 2|12 pages
Ecology of Antibiotic Resistance Genes
View abstract
chapter 3|22 pages
Global Response Systems That Confer Resistance
View abstract
chapter 4|26 pages
Multidrug Effl ux Pumps: Structure, Mechanism, and Inhibition
View abstract
chapter 5|32 pages
Mechanisms of Aminoglycoside Antibiotic Resistance
View abstract
chapter 6|30 pages
Resistance to β-Lactam Antibiotics Mediated by β-Lactamases: Structure, Mechanism, and Evolution
View abstract
chapter 7|36 pages
Target Modifi cation as a Mechanism of Antimicrobial Resistance
View abstract
chapter 8|14 pages
Antibiotic Permeability
View abstract
chapter 9|46 pages
Genetic Methods for Detecting Bacterial Resistance Genes
View abstract
chapter 10|26 pages
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
View abstract
chapter 11|36 pages
Antimicrobial Resistance in the Enterococcus
View abstract
chapter 12|22 pages
Methicillin Resistance in Staphylococcus aureus
View abstract
chapter 13|30 pages
Mechanism of Drug Resistance in Mycobacterium tuberculosis
View abstract
chapter 14|20 pages
Antibiotic Resistance in Enterobacteria
View abstract
chapter 15|14 pages
Resistance as a Worldwide Problem
View abstract
chapter 16|32 pages
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
View abstract
chapter 17|10 pages
Antibacterial Drug Discovery in the 21st Century
View abstract
CONTENTS
ABOUT THIS BOOK

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Unde

TABLE OF CONTENTS
chapter 1|10 pages
Microbial Drug Resistance: A Historical Perspective
View abstract
chapter 2|12 pages
Ecology of Antibiotic Resistance Genes
View abstract
chapter 3|22 pages
Global Response Systems That Confer Resistance
View abstract
chapter 4|26 pages
Multidrug Effl ux Pumps: Structure, Mechanism, and Inhibition
View abstract
chapter 5|32 pages
Mechanisms of Aminoglycoside Antibiotic Resistance
View abstract
chapter 6|30 pages
Resistance to β-Lactam Antibiotics Mediated by β-Lactamases: Structure, Mechanism, and Evolution
View abstract
chapter 7|36 pages
Target Modifi cation as a Mechanism of Antimicrobial Resistance
View abstract
chapter 8|14 pages
Antibiotic Permeability
View abstract
chapter 9|46 pages
Genetic Methods for Detecting Bacterial Resistance Genes
View abstract
chapter 10|26 pages
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
View abstract
chapter 11|36 pages
Antimicrobial Resistance in the Enterococcus
View abstract
chapter 12|22 pages
Methicillin Resistance in Staphylococcus aureus
View abstract
chapter 13|30 pages
Mechanism of Drug Resistance in Mycobacterium tuberculosis
View abstract
chapter 14|20 pages
Antibiotic Resistance in Enterobacteria
View abstract
chapter 15|14 pages
Resistance as a Worldwide Problem
View abstract
chapter 16|32 pages
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
View abstract
chapter 17|10 pages
Antibacterial Drug Discovery in the 21st Century
View abstract

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Unde

TABLE OF CONTENTS
chapter 1|10 pages
Microbial Drug Resistance: A Historical Perspective
View abstract
chapter 2|12 pages
Ecology of Antibiotic Resistance Genes
View abstract
chapter 3|22 pages
Global Response Systems That Confer Resistance
View abstract
chapter 4|26 pages
Multidrug Effl ux Pumps: Structure, Mechanism, and Inhibition
View abstract
chapter 5|32 pages
Mechanisms of Aminoglycoside Antibiotic Resistance
View abstract
chapter 6|30 pages
Resistance to β-Lactam Antibiotics Mediated by β-Lactamases: Structure, Mechanism, and Evolution
View abstract
chapter 7|36 pages
Target Modifi cation as a Mechanism of Antimicrobial Resistance
View abstract
chapter 8|14 pages
Antibiotic Permeability
View abstract
chapter 9|46 pages
Genetic Methods for Detecting Bacterial Resistance Genes
View abstract
chapter 10|26 pages
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
View abstract
chapter 11|36 pages
Antimicrobial Resistance in the Enterococcus
View abstract
chapter 12|22 pages
Methicillin Resistance in Staphylococcus aureus
View abstract
chapter 13|30 pages
Mechanism of Drug Resistance in Mycobacterium tuberculosis
View abstract
chapter 14|20 pages
Antibiotic Resistance in Enterobacteria
View abstract
chapter 15|14 pages
Resistance as a Worldwide Problem
View abstract
chapter 16|32 pages
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
View abstract
chapter 17|10 pages
Antibacterial Drug Discovery in the 21st Century
View abstract
ABOUT THIS BOOK
ABOUT THIS BOOK

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Unde

TABLE OF CONTENTS
chapter 1|10 pages
Microbial Drug Resistance: A Historical Perspective
View abstract
chapter 2|12 pages
Ecology of Antibiotic Resistance Genes
View abstract
chapter 3|22 pages
Global Response Systems That Confer Resistance
View abstract
chapter 4|26 pages
Multidrug Effl ux Pumps: Structure, Mechanism, and Inhibition
View abstract
chapter 5|32 pages
Mechanisms of Aminoglycoside Antibiotic Resistance
View abstract
chapter 6|30 pages
Resistance to β-Lactam Antibiotics Mediated by β-Lactamases: Structure, Mechanism, and Evolution
View abstract
chapter 7|36 pages
Target Modifi cation as a Mechanism of Antimicrobial Resistance
View abstract
chapter 8|14 pages
Antibiotic Permeability
View abstract
chapter 9|46 pages
Genetic Methods for Detecting Bacterial Resistance Genes
View abstract
chapter 10|26 pages
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
View abstract
chapter 11|36 pages
Antimicrobial Resistance in the Enterococcus
View abstract
chapter 12|22 pages
Methicillin Resistance in Staphylococcus aureus
View abstract
chapter 13|30 pages
Mechanism of Drug Resistance in Mycobacterium tuberculosis
View abstract
chapter 14|20 pages
Antibiotic Resistance in Enterobacteria
View abstract
chapter 15|14 pages
Resistance as a Worldwide Problem
View abstract
chapter 16|32 pages
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
View abstract
chapter 17|10 pages
Antibacterial Drug Discovery in the 21st Century
View abstract

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Unde

TABLE OF CONTENTS
chapter 1|10 pages
Microbial Drug Resistance: A Historical Perspective
View abstract
chapter 2|12 pages
Ecology of Antibiotic Resistance Genes
View abstract
chapter 3|22 pages
Global Response Systems That Confer Resistance
View abstract
chapter 4|26 pages
Multidrug Effl ux Pumps: Structure, Mechanism, and Inhibition
View abstract
chapter 5|32 pages
Mechanisms of Aminoglycoside Antibiotic Resistance
View abstract
chapter 6|30 pages
Resistance to β-Lactam Antibiotics Mediated by β-Lactamases: Structure, Mechanism, and Evolution
View abstract
chapter 7|36 pages
Target Modifi cation as a Mechanism of Antimicrobial Resistance
View abstract
chapter 8|14 pages
Antibiotic Permeability
View abstract
chapter 9|46 pages
Genetic Methods for Detecting Bacterial Resistance Genes
View abstract
chapter 10|26 pages
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
View abstract
chapter 11|36 pages
Antimicrobial Resistance in the Enterococcus
View abstract
chapter 12|22 pages
Methicillin Resistance in Staphylococcus aureus
View abstract
chapter 13|30 pages
Mechanism of Drug Resistance in Mycobacterium tuberculosis
View abstract
chapter 14|20 pages
Antibiotic Resistance in Enterobacteria
View abstract
chapter 15|14 pages
Resistance as a Worldwide Problem
View abstract
chapter 16|32 pages
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
View abstract
chapter 17|10 pages
Antibacterial Drug Discovery in the 21st Century
View abstract
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