ABSTRACT
Over the last 20 years, our experience at the University of British Columbia Orbital Clinic in managing over 6000 orbital cases has led to a paradigm shift in terms of understanding orbital inflammatory disease. This is characterized by broad clinical definitions of inflammations shifting to diagnoses that are based on pathologic, anatomic, and systemic associations of disease. In recent years, we have seen increasing diagnostic specificity brought about by immunopathologic and molecular techniques, which in turn will link to specific treatment based on disease pathogenesis (1).
