ABSTRACT
This chapter starts the discussion on scalable single-cell analysis. It presents a research vision to design a large-scale cyber-physical system experimental framework to enable collaborative and coordinated single-cell molecular biology studies. This framework will be based on the integration of cyber-physical systems with microfluidic biochips and cloud computing. It has the potential to drastically advance personalized medicine through knowledge fusion among many research groups, and synchronization of research planning. This framework therefore leads to a better understanding of diseases such as cancer, and helps researchers in identifying effective treatments. A case study from cancer research is discussed to explain the significance of our automation framework in promoting coordinated genomic studies.
