ABSTRACT
Continuous manufacturing of pharmaceuticals, including aspects of modern process development is highlighted in this book with both the ‘why’ and the ‘how’, emphasizing process modeling and process analytical technologies. Presenting specific case studies and drawing upon extensive experience from industry and academic opinion leaders, this book focuses on the practical aspects of continuous manufacturing. It gives the readers the strategic perspective and technical depth needed to adopt and implement these technologies, where appropriate, in order to gain the competitive edge in speed, agility, and reliability.
Features:
- Discusses scientific solutions and process analytical technology to enable continuous manufacturing in the development of new drugs
- Includes short stories about how some companies have adopted CM and what their drivers were and what benefits were realized
- Addresses economic and practical considerations, unlike many other technical books
- Emphasizes the practical aspects to give the reader the strategic imperative and technological depth to adopt and implement these technologies
- Highlights the "why" and the "how", focusing on the need analysis and process modeling and process analytical technologies
TABLE OF CONTENTS
part I|270 pages
Design and Control
chapter 1|83 pages
A Survey of Continuous API Syntheses
part II|37 pages
Design and Control
chapter 8|12 pages
Continuous Manufacturing of Biologics Drug Products
chapter 9|23 pages
Modernizing Manufacturing of Parenteral Products
part III|63 pages
Process Analytical Technologies
chapter 12|17 pages
Moving to Manufacturing
part IV|103 pages
Modeling, Design Space, and Future Outlook