ABSTRACT

Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.

Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery.

Additional features include"

  • Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing.
  • Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize.
  • Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario
  • Discusses siRNA, mRNA, and DNA plasmids.

 

chapter 2|16 pages

Advances in Genome Editing

The Technology of Choice for Precise and Efficient Disease Treatment, with Special Focus on Nano Delivery Systems

chapter 3|20 pages

Extracellular Vesicles for Nucleic Acid Delivery

Progress and Prospects for Safe RNA-Based Gene Therapy