ABSTRACT

This book introduces transdermal drug delivery and the developments that have taken place in various transdermal drug delivery techniques including the system-level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the microelectromechanical systems (MEMS)-based fabrication technique and the design, fabrication and characterization of different MEMS-based components like microneedles and micropumps. It further includes a MEMS-based component micropump with design, analysis, fabrication and characterization of the transdermal drug delivery device and challenges encountered in the design improvements.

Features:

  • Summarizes transdermal drug delivery systems especially with a focus on MEMS and microneedles, including theoretical concepts
  • Emphasizes system integration by describing simulation and design techniques as well as experimental fabrication
  • Discusses system-level integration for miniaturized therapeutic devices
  • Includes working simulation models covering microneedles and micropump analysis
  • Explores future direction in development of pertinent devices

The book is aimed at researchers, professionals, and graduate students in biomedical engineering, microelectronics, micro-electro-mechanical-systems, and drug delivery.

chapter 1|16 pages

Transdermal Drug Delivery Systems

chapter 2|13 pages

At the Bottom

Microfluidics and Scaling Laws

chapter 3|28 pages

Microneedles

New Tools of Painless Interface to Skin

chapter 5|29 pages

Design and Simulation of Microneedles

chapter 8|21 pages

Micropumps for Drug Delivery

chapter 9|20 pages

Piezoelectric Actuator-based Micropumps