ABSTRACT

Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery. 

This book highlights the increased attention that the recent spectacular advances in gene therapy and nanotechnology have brought to dosage form design and drug delivery. With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever.

Apart from revising and updating existing chapters on the basic principles, this edition highlights the emerging emphasis on drug discovery, antibodies and antibody-drug conjugates as therapeutic moieties, individualized medicine including patient stratification strategies, targeted drug delivery, and the increasing role of modeling and simulation.

Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors and professionals, saving their time and money.

part I|143 pages

Introductory chapters

chapter 1|21 pages

Drug discovery

chapter 2|23 pages

Drug development

chapter 3|19 pages

Pharmaceutical considerations

chapter 4|22 pages

Biopharmaceutical considerations

chapter 5|53 pages

Pharmacy math and statistics

part II|240 pages

Physicochemical principles

chapter 6|22 pages

Complexation and protein binding

chapter 7|33 pages

Chemical kinetics and stability

chapter 8|17 pages

Interfacial phenomena

chapter 9|19 pages

Colloidal dispersions

chapter 10|21 pages

Surfactants and micelles

chapter 11|23 pages

Pharmaceutical polymers

chapter 12|11 pages

Rheology

chapter 13|13 pages

Radiopharmaceuticals

chapter 14|23 pages

Drug delivery systems

chapter 15|48 pages

Organ-specific drug delivery

part III|248 pages

Dosage forms

chapter 16|19 pages

Suspensions

chapter 17|17 pages

Emulsions

chapter 18|12 pages

Pharmaceutical solutions

chapter 19|41 pages

Powders and granules

chapter 20|30 pages

Tablets

chapter 21|23 pages

Capsules

chapter 22|13 pages

Parenteral drug products

chapter 23|16 pages

Semisolid dosage forms

chapter 24|19 pages

Inserts, implants, and devices

chapter 25|33 pages

Protein and peptide drug delivery

chapter 26|16 pages

Biotechnology-based drugs