ABSTRACT

Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the obesity and metabolic syndrome epidemics, which this up-to-date book deals with comprehensively. The contents outline disease mechanisms, diagnostic tests, management, varying manifestations, and special populations. It covers the mechanistic pathways that contribute to NAFLD development, including the role of genetic variants and the gut microbiome. It elaborates on noninvasive diagnostic tests to screen for NAFLD, determine its severity, and monitor response to lifestyle intervention and pharmacologic treatment. This book helps clinicians diagnose and treat this common and potentially deadly disease.

Key Features:

  • Reviews current drugs in development and provides practical advice to clinicians on the diagnosis and management of fatty liver.
  • Proves attractive to primary care providers who are on the front line of managing patients with NAFLD, to gastroenterologists and hepatologists who would benefit from updated data on how to risk-stratify patients and identify those who will be eligible for pharmacologic treatment, and other specialists such as cardiologists, endocrinologists, and nephrologists who will find this book to be a useful reference on the extrahepatic manifestations of NAFLD.
  • Focuses on extrahepatic manifestations and new insights on the mechanistic drivers of the disease.

section Section II|38 pages

Diagnostic Tests

section Section III|70 pages

Management

chapter 10|8 pages

Dietary Interventions

chapter 14|15 pages

PPAR Agonists

chapter 15|9 pages

Anti-Inflammatory Drugs

Metabolic Inflammation in NASH—A Drug Target?

section Section IV|34 pages

Extrahepatic Manifestations

section Section V|39 pages

NAFLD in Special Populations

chapter 21|7 pages

NAFLD in Children

Unique Aspects and Controversies

chapter 22|12 pages

NAFLD in HIV Patients