ABSTRACT

Psychiatric symptoms have been attributed to a conflicted mind (Freud, 1900), problems in living (Szasz, 1961) or, more recently, a “broken brain” (Andreasen, 1984). With the advent of advanced, non-invasive imaging technologies like computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), a longstanding interest in identifying the specifics of the broken brain has been renewed (Weinberger, Wagner and Wyatt, 1983; Andreasen et al., 1986; Kling, Metter, Riege and Kuhl, 1986). Besides serving a heuristic purpose, these studies are important for their potential to subdivide the “group of schizophrenias” (Bleuler, 1911/1950) into discrete, clinically viable syndromes.