ABSTRACT
The notion that traumatic brain injury (TBI) can be a relevant etiological factor in the onset of schizophrenia has been an ongoing source of debate in the literature. Despite this, systematic studies have been limited. While a handful of studies have failed to find an increased risk of schizophrenia (see for example, Harrison et al., 2006), a majority of studies support an increased prevalence of psychosis in individuals who have had a TBI. Psychiatric disorders of many types have been reported to be a major cause of disability after TBI. Major depression is the most studied psychiatric disorder, with occurrence rates estimated to be 14%–77% after TBI. Psychotic disorders including schizophrenia and syndromes referred to as schizophrenia-like psychosis (SLP) have been reported to occur more frequently in persons who have had a TBI than in the general population.
