ABSTRACT
Speirs V, Malone C, Walton DS, Kerin MJ, Atkin SL. Increased expression of estrogen receptor b-mRNA in tamoxifen resistant breast cancer patients. Cancer Research 1999; 59:5421-5424.
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The great strength of this article lay in the development of a recombinant receptor critical for innumerable chemical and mechanistic studies. The exact definition of receptor function became possible by gene transfer to receptor-negative cells.
