ABSTRACT
This paper summarizes the experience of a blinded evaluation of breast cancer screening using whole-breast ultrasound. 1140 women underwent a clinical breast examination, X-ray mammography, and whole-breast ultrasound evaluation using state-of-the-art equipment. Each study was blinded to the results of the other so that the separate contribution of each could be established. It was demonstrated that ultrasound was less sensitive than mammography in detecting breast cancer and that ultrasound screening resulted in an unacceptably high false-positive rate with no increase in cancer detection.
