ABSTRACT

Radiotherapy plays an important role in the treatment of patients with plasma cell tumors. Radiotherapy may be delivered for the following reasons:

● definitive treatment for potential cure of patients with solitary plasmacytoma;

● in combination with chemotherapy in patients with systemic disease;

● as part of a pre-transplant conditioning regimen in the form of total-body irradiation;

● for palliation of pain, neurologic compromise, or structural instability from focal disease.