ABSTRACT
Light-chain deposition disease (LCDD) represents a monoclonal plasma cell dyscrasia that is characterized by the presence of punctate or granular, electron-dense, homogeneous lightchain immunoglobulin (Ig) molecules in basement membranes of the kidney and other vital organs.1-7 The relentless progression of this deposition eventually leads to renal, cardiac, or hepatic failure, and accounts for the poor prognosis of patients with this illness.8
