Clinical and pathologic correlates

Desmoids in the presence of familial polyposis Clinical desmoids occur in approximately 10% of all patients with familial adenomatous polyposis (FAP). Intra-abdominal desmoids are highly unpredictable, but, as opposed to desmoids in the extremity, can ultimately result in the death of the patient. Unfortunately, the morbidity of operation, radiation and chemotherapy in such patients is very significant.