ABSTRACT

In 1832, Thomas Hodgkin produced a treatise entitled ‘On some morbid appearances of the absorbent glands and spleen’ which gave an account of 7 patients who had lymphnode enlargement without evidence of current infection [1]. With time, the histology of such lymph-node enlargements was elucidated, and the presence of the so-called ReedSternberg cells and their mononuclear counterparts was identified as a characteristic feature of the malignant disease that had become known as Hodgkin’s disease [2-4].