ABSTRACT

Acquired Immune Deficiency Syndrome (AIDS) is a specific group of diseases or conditions that indicate severe immunosuppression related to infection with the human immunodeficiency virus (HIV) …

The immunodeficiency that occurred in AIDS patients was measurably different from immunological disorders previously recognised in adults. Severe and apparently irreversible, the immunodeficiency predisposed these individuals to frequent and devastating infections. The immunological deficiency appeared to be qualitatively different in that previously uncommon entities, such as aggressive multifocal Kaposi’s sarcoma, disseminated Mycobacterium avium infections, chronic enteric cryptosporidiosis, and disseminated toxoplasmosis, all were unusually common compared to other immunosuppressed populations.