ABSTRACT

Fracture healing is a specialized form of tissue healing and similar to other histopathological repair processes. An understanding of normal bone formation and structure is essential. Bone consists of mesenchymal cells embedded in a mineralized extracellular matrix for strength and stiffness, with type I collagen predominating. The periosteum, with an inner cambium or vascular layer and outer fibrous layer, plays a vital role in fracture healing.