ABSTRACT
Karl Lashley was probably the first researcher to study learning in the brain systematically. He believed that memory was a feature of the cortex and set about trying to discover where this function resided. For some researchers, the idea of trying to understand the complexities of mammalian memory is too far. These researchers have opted to try to explore the biochemical underpinnings of memory in invertebrates. Donald Hebb also believed in a distributed memory system and his ideas are the foundation of one form of modern-day connectionist architecture. This principle of parallel distributed processing is in direct opposition to the idea of the engram. Long-term potentiation was first discovered by T. V. P. Bliss and T. Lomo. They found that if the perforant pathway in the entorhinal cortex of the brain was repeatedly stimulated at a fast rate then the responses to a single stimulus in the receiving dentate gyrus of the hippocampus would be potentiated.
