ABSTRACT
The issue of prevention and treatment of restenosis, whether it occurs following balloon angioplasty, stent insertion, or other therapeutic endeavour, is the goal of the scientist involved in the management of coronary artery disease. The invaluable legacy of Andreas Gruntzig and John Simpson in the pioneering work that initiated the practice of coronary angioplasty, and spawned all of the interventional techniques and practices of today, is only held back by the remaining major issue of restenosis. This remaining barrier leads to negative impact on patients and health economics.
