ABSTRACT
Most cholesterol in human plasma is carried
bound to apoB100, contributing about 50% of
the mass of each particle. The primary role of
LDL is the transport of both dietary and
endogenously synthesized cholesterol to
peripheral tissues for use in the manufacture of
cell membranes and steroid hormones. The
cholesterol content of atherosclerotic plaques is
largely derived from LDL, but these
lipoproteins may need to be oxidatively
damaged in order to be atherogenic.
