ABSTRACT

A hydatidiform mole with a coexisting live fetus is a rare entity. Suspicion may arise when an ultrasound scan identifies a fetal pole along an abnormal placenta. The main issue is to differentiate between two diagnoses: a singleton pregnancy consisting of a partial hydatidiform mole with an abnormal triploid fetus which usually dies in utero during the first half of pregnancy; and a twin gestation consisting of a complete hydatidiform mole along with a coexisting live fetus (CMCF). The latter is extremely rare1-4, and management is challenging because the fetus may be viable. Information about this entity is scant. Moreover, only a few case reports of a twin gestation with a coexisting hydatidiform mole have accurately distinguished between a partial mole with a live fetus and CMCF. Although CMCF is associated with fetal survival, it carries a significant risk of severe complications such as pre-eclampsia, preterm delivery and development of persistent gestational trophoblastic tumor (GTT).