ABSTRACT
Over recent years in several developed countries, younger women have demonstrated substantial declines in ovarian cancer incidence and mortality1-4.
Cohort analyses based on data from Switzerland5, Britain6, Sweden7, England and Wales8 and The Netherlands9, as well as systematic analyses of mortality trends in 16 major European countries2,3,10 and in the USA11, showed that women born from 1920 onwards, i.e. the generations who had used oral contraceptives (OCs), demonstrated consistently reduced ovarian cancer rates. The downward trends were larger in countries where OCs had been more widely utilized3.
