ABSTRACT
Essential for good compliance with hormone replacement therapy (HRT) is the appropriate choice of estrogen and progestin, their dosage and the form of administration. An individual approach to the choice of drug is the first condition of successful long-term therapy. Treatment has to be efficacious, with a minimum of adverse side-effects. Ineffectual treatment with adverse side-effects often results in withdrawal within the first month of therapy. This may engender distrust or fear, and, as a consequence, permanent refusal of such treatment. Not only is the appropriate choice of drug, dose and form of administration necessary, but also full information on possible adverse side-effects, which for the most part disappear within the first 3 months of treatment.
