ABSTRACT

Schizophrenia is a debilitating disorder of brain function with genetic and environmental susceptibilities.! A growing body of epidemiologic evidence supports a neurodevelopmental origin for this disorder.2 These studies link prenatal human influenza viral infection with a subsequent rise in schizophrenic births. Experimental animal data supporting this linkage are lacking. The studies described in this chapter discuss data concerning an animal model of post-viral behavioral disorder caused by prenatal exposure to human influenza virus (InN).