ABSTRACT
Despite intensive study for well over a century, renal cell carcinoma (RCC) continues to rank as one of the most enigmatic malignancies. Our understanding of the molecular genetics of RCC remains in its infancy and, although surgical interventions for localized disease are often successful, definitive therapeutics for advanced disease remains elusive. As witnessed by several recent reviews on RCC, the significance of management of this difficult cancer remains at the forefront of modern medicine 1-4 . Herein we examine the fundamental information concerning RCC with an emphasis on its surgical management.
