ABSTRACT
Treatment of in-stent restenosis is frequently a challenging clinical problem, with recurrent restenosis being reported in up to 80% in the most complex cases.4 Currently, vascular brachytherapy is the only strategy proven to be more effective for the treatment of in-stent restenosis than other conventional approaches.167-171 However, post-brachytherapy recurrent restenosis has been reported to occur in 17% to 32% of patients at 1 year.167-171 Moreover, despite the relative improvement in outcomes, brachytherapy has not been extensively adopted as routine therapy in many centers, mostly because of logistic and technical limitations.
