ABSTRACT

Several reports have previously evaluated the impact of baseline and procedural characteristics on the risk of subsequent restenosis after bare metal stent implantation, with a number of high-risk parameters, such as diabetes, lesion length, and vessel size, being consistently identified in most studies.1-3,35,128,201,202 Unfortunately, these characteristics are commonly found in daily practice, where treatment of patients with complex lesions frequently appears as a challenging therapeutic dilemma. In the present chapter, highly complex patients treated with sirolimus-eluting stent (SES) in the RESEARCH were evaluated for the presence of post-SES restenosis. The value of clinical, angiographic, and procedural factors in predicting the risk of restenosis in this population is evaluated.