ABSTRACT

Posterior capsule opacification (PCO) a major post-operative complication following cataract surgery occurs in 20 to 50% of adult patients. Migration and proliferation of lens epithelial cells (LECs) onto the posterior capsule is considered the primary step in two major forms of PCO, posterior capsular fibrosis and Elshnig pearls. Inflammatory cells also plays a role in formation of PCO, in patients who have significant postoperative inflammation following cataract surgery.