ABSTRACT
Over 80% of multiple sclerosis (MS) patients have symptoms of lower genitourinary tract dysfunction. More than 96% of patients with the disease for 10 years will have had urological manifestations.[1-4] The effect of MS on the genitourinary tract can range from bladder and urethral dysfunction to impotence. Consequently, genitourinary symptoms can be a source of considerable frustration and distress for the patient with MS; urologic involvement presents most commonly as either lower urinary tract (bladder and urethral) dysfunction (LUTD) or sexual dysfunction. Because LUTD and sexual dysfunction can have a significant impact on quality of life, a working knowledge of the pathophysiology, evaluation, and treatment of these conditions is essential for the MS specialist, who is often called upon to manage these severe, debilitating symptoms.
