ABSTRACT
The pathophysiology of chronic compartment syndrome describes how abnormally increased intramuscular pressure in a compartment affects muscle blood ßow, tissue oxygenation, and neuromuscular function.1–3 It also includes the study of how patients are affected by local muscular ischemia4,5 and exercise-induced pain. Basic understanding of the pathophysiology of chronic compartment syndrome enhances the ability to diagnose this syndrome by clinical means as well as the understanding of other conditions of chronic leg pain.
