ABSTRACT

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INTRODUCTION

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MATERIALS AND METHODS

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Histology

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TISSUE

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Preparation of Te

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VIABILITY ASSAY-MTT ET-50 METHOD

f Tissue

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Exposure Times

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st Article to EpiOcular Tissue

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rticle from EpiOcular Tissue

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TT Assay

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Calculation of Ef

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Determination of

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Testing of Predic

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fective Time 50 (ET-50)

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Prediction Model

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tion Model

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esting

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sting

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Testing of Ultram

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Histological Char

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RESULTS

acterization of the EpiOcular Tissue Model

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A

B

Determination of

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Testing of Predic

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Prediction Model

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OCL-200 Prediction Equation

ET-50 (min)

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Interlaboratory R

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Testing of Ultram

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esults: 1996-2000

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eproducibility

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