ABSTRACT

The visual transduction process in rod photoreceptor cells for scotopic vision begins with absorption of a photon by a rhodopsin molecule, which is a seven-transmembrane

α

-helical protein having 11-

cis

- retinal as a chromophore. Light isomerizes the 11-

cis

-retinal into all-

trans

form,

resulting in conformational changes of the protein moiety to form an enzymatically active intermediate, metarhodopsin II (meta II).