ABSTRACT
Skin is a vital organ, in the sense that the loss of substantial fraction of its mass immediately threatens the life of the individual. A cutaneous wound is any loss of skin integrity. Such a loss can result suddenly, either from fire or mechanical accident, or it can occur in a chronic manner due to illness, as in skin ulcers. Since intact skin is of vital importance to protect the organism against environment, regenerative mechanisms must be activated to resolve a defect. Cutaneous wound healing is a dynamic biological process that begins with tissue injury. It has several goals:
The discontinuation of further injury The recruitment of injured cells The formation of new tissue The remodeling of the new tissue to best approximate the preinjury form and function. These events have traditionally been divided into three overlapping phases: an inflammatory phase,
a proliferative phase, and a maturation phase.
