ABSTRACT
Biochemical studies with Plasmodium began with the work of J.D.Fulton and S.R. Christophers in 1938, and, in the half-century since, there have been more than a dozen reviews summarizing the progress made (Fulton, 1951; McKee, 1951; Fulton and Spooner, 1955; Moulder, 1948, 1962; Honigberg, 1967; Peters, 1969; Trager, 1970; Fletcher and Maegraith, 1972; Oelshlegel and Brewer, 1975; Homewood, 1978; Homewood and Neame, 1980; Sherman, 1979, 1984; Scheibel, 1988; Scheibel and Sherman, 1988; Trigg, 1988; Fairlamb, 1989). Although the present review is based on these earlier works, it is not intended to be a recapitulation of what has already been written. Rather, this overview is an attempt to summarize and critically evaluate the published work on the biochemistry of the blood stages of malaria that appeared in print between 1984 and July 1990, with special emphasis on the human malarial parasite P. falciparum.
