ABSTRACT

The threshold for typical psychic effects of cannabis lies in the range of about 0.2 to 0.3 mg j},9_ THC/kg body weight or 5 to 10 mg/m2 body surface area, respectively, or about 10 to 15 mg THC in an adult. However, this threshold may occasionally be lower, 5 mg THC per single dose, particularly in older individuals. Pronounced psychic effects after oral application are expected above 0.4 mg/kg. With inhalation, the threshold for perceivable effects may be lower, 5 mg or less.