ABSTRACT

Multiple replicons In eukaryotes, replication of chromosomal DNA occurs only in the S phase of the cell cycle (Section A3). As for bacterial DNA (Section F3), eukaryotic DNA is replicated semiconservatively. Replication of each linear DNA molecule in a chromosome starts at many origins, one every 30-300 kilobases (kb) of DNA depending on the species and tissue, and proceeds bi-directionally from each origin.