ABSTRACT
CASE PRESENTATION This patient developed a rest tremor of the left hand at age 28 followed by left-sided rigidity. Within 1 year, tremor appeared on the right side also with rigidity. These symptoms, along with bradykinesia, progressed, and a diagnosis of Parkinson’s disease (PD) was made. Two years after the first symptom appeared, carbidopa/levodopa was started. There was a marked response and the patient was almost symptom-free for 3 years, the so-called ‘honeymoon period’. Motor fluctuations then developed, with peak-dose dyskinesias. As the disease progressed the ‘on’ periods shortened, the ‘off’ periods lengthened, and the dyskinesias became violent.
