ABSTRACT

CASE PRESENTATION A 62-year-old man was diagnosed with Parkinson’s disease in 1993 and treated with amantadine, benztropine, and carbidopa/levodopa. Three years later, due to adverse effects and inadequate efficacy, amantadine and benztropine were eliminated and pergolide was begun. Within 9 months, the dose of pergolide was adjusted to 1 mg three times daily and he was able to reduce the dose of controlled/release carbidopa-levodopa 50/200 from one to one-half tablet three times a day. Following the addition of pergolide, his left hand resting tremor and rigidity resolved and his left hand bradykinesia improved.