ABSTRACT
CASE PRESENTATION A 48-year-old woman with an 8-year history of multiple sclerosis (MS) was referred for a movement disorder. MS presented with optic neuritis and paresthesias of the feet. Three years later, she experienced severe gastroparesis requiring a feeding tube, and she was placed on metoclopramide. Approximately 1 year later she began having involuntary trunk and hip movements described as ‘swaying’. She subsequently developed orofacial dyskinesias and she was diagnosed as having tardive dyskinesia. The metoclopramide was stopped and she was put on tetrabenazine which helped, but only for about 6 months. She was next treated with risperiodone followed by clozapine, but the movements persisted and were severe enough to affect her gait, and she limited her social activities because of embarrassment. At the time of the initial visit, the movements had been present continuously during her waking hours for the past 4 years.
