ABSTRACT
Neuropathological conditions caused by the degeneration of neuronal cells have been considered incurable because of a long-held ‘truism’: neurons do not regenerate during adulthood. However, this statement has been challenged and we have found new evidence that neurons do indeed have the potential to be renewed after maturation. The discovery of multipotent neural stem cells (NSCs) in the adult brain1,2 has brought revolutionary changes in the theory of neurogenesis, which currently posits that regeneration of neurons can occur throughout life, thus opening a door for the development of novel therapies to treat neurodegenerative diseases by neuronal regeneration using stem cell transplantation.
