ABSTRACT
Other common trade names: Aldopur; Almatol; Diram; Merabis; Novo-Spiroton; Osiren; Spiroctan; Tensin Indications: Hyperaldosteronism, hirsutism, hypertension Category: Diuretic; Potassium-sparing antihypertensive diuretic Half-life: 78-84 minutes Clinically important, potentially hazardous interactions with: amiloride, benazepril, captopril, cyclosporine, enalapril, fosinopril, juniper, lisinopril, mitotane, moexipril, potassium iodide, quinapril, ramipril, trandolapril, triamterene
Aldactazide is spironolactone and hydrochlorothiazide
Reactions
Skin Bullous pemphigoid [1] Chills Chloasma [1] Dermatitis [6] Diaphoresis Eczema [2] Erythema Erythema annulare centrifugum [1] Erythema multiforme [1] Exanthems (<5%) [6] Facial edema [1] Flushing (<1%) Graft-versus-host reaction [1] Lichen planus [1] Lichenoid eruption [2] Lupus erythematosus [2] Melasma [2] Necrotizing vasculitis Pemphigus [2] Photosensitivity Pigmentation [4] Pruritus [2]
Purpura Rash (sic) (1-10%) [2] Raynaud’s phenomenon [1] Side effects (sic) [1] Urticaria [2] Vasculitis [1] Xerosis (40%) [3]
Hair Hair – alopecia [2] Hair – hirsutism
Other Acute intermittent porphyria Ageusia Anaphylactoid reactions DRESS syndrome [1] Gynecomastia (<1%) [11] Headache Mastodynia [1] Oral lichen planus [1] Paresthesias Xerostomia
