ABSTRACT

Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain, dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production, distribution and actions of this very important molecule.

Key Features:

  • Explores the many different faces of dopamine as autocrine, paracrine and endocrine molecule
  • Documents the adverse effects of antipsychotics on dopamine functions
  • Reviews the many ways dopamine affects the cardiovascular, renal and reproductive systems
  • Provides updates on receptor oligomerization and signaling
  • Examines the role of dopamine in tumorigenesis

Related Titles

Jones, S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4)

Luo, L. Principles of Neurobiology (ISBN 978-0-8153-4494-0)

Sidhu, A. et al., eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2)

chapter 1|26 pages

Homeostasis of Dopamine

chapter 4|38 pages

Endocrine Functions of Brain Dopamine

chapter 10|45 pages

Regulation of Reproduction by Dopamine

chapter 13|29 pages

Involvement of Dopamine with Various Cancers