ABSTRACT

The risks involved in introducing new drugs and devices are amongst the most discussed issues of modern medicine.

Presenting a new way of thinking about these issues, this volume considers risk and medical innovation from a social historical perspective, and studies specific cases of medical innovation, including X-rays, the pill and Thalidomide, in their respective contexts.

International cases are examined through the lens of a particular set of shared questions - highlighting differences, similarities, continuities and changes, and offering a historical sociology of risk. Particularly important is the re-conceptualization of dangers in terms of risk - a numerical and probabilistic approach allowing for seemingly objective and value-neutral decisions.

Read together, these papers add to our understanding of the current debate about risk and safety by providing a comparative background to the discussion, as well as a set of generally applicable criteria for analyzing and evaluating the contemporary issues surrounding medical innovation.

chapter 1|17 pages

Risk and Medical Innovation

A historical perspective

chapter 2|17 pages

To Assess and To Improve

Practitioners' Approaches to Doubts Linked with Medical Innovations 1720–1920

chapter 4|17 pages

Redemption, Danger and Risk

The History of Anti-bacterial Chemotherapy and the Transformation of Tuberculin

chapter 5|21 pages

“As Safe as Milk or Sugar Water”

Perceptions of the Risks and Benefits of the BCG Vaccine in the 1920s and 1930s in France and Germany

chapter 6|21 pages

From Danger to Risk

The perception and regulation of X-rays in Switzerland, 1896–1970 1

chapter 7|15 pages

The Population as Patient

Alice Stewart and the Controversy Over Low-level Radiation in the 1950s

chapter 8|13 pages

To Treat or Not to Treat

Drug Research and the Changing Nature of Essential Hypertension

chapter 9|19 pages

Hormones at Risk

Cancer and the Medical Uses of Industrially-produced Sex Steroids in Germany, 1930–1960

chapter 11|16 pages

Assessing the Risk and Safety of the Pill

Maternal Mortality and the Pill

chapter 12|18 pages

Addressing Uncertainties

The Conceptualization of Brain Death in Switzerland 1960–2000 1

chapter 13|16 pages

Risk on Trial

The Interaction of Innovation and Risk in Cancer Clinical Trials

chapter 14|18 pages

BioRisk: Interleukin-2 from Laboratory to Market in the United States and Germany

Practitioners' Approaches to Doubts Linked with Medical Innovations 1720–1920

chapter 15|18 pages

The Redemption of Thalidomide

Standardizing the Risk of Birth Defects 1