ABSTRACT
The larynx is affected by a variety of tumors, chief among which are squamous cell carcinoma (SCC), adenocarcinoma, neuroendocrine tumor, and sarcoma. Laryngeal SCC develops in the thin, flat, scalelike cells that line much of the larynx and accounts for 95" of laryngeal cancer reported. Based on tumor location, laryngeal SCC may be separated into glottic, supraglottic, subglottic, and transglottic SCC. Risk factors for laryngeal cancer include cigarette smoking, excess alcohol consumption, aging, vitamin A deficiency, exposure to asbestos, poor dental hygiene, human papillomavirus (HPV) infection, and presence of squamous cell cancers in the upper aerodigestive tract. Diagnostic procedures for laryngeal cancer include physical exam, medical history review, imaging, biopsy, histopthological assessment and molecular testing. Treatment for laryngeal cancer involves surgery, radiotherapy, or chemotherapy, alone or in combination. The stages of laryngeal cancer range from 0, I, II, III, to IV.
