ABSTRACT

The study was aimed to determine factors affecting mortality among hemodialysis patients. This was a prospective observational study of adult hemodialysis patients from twelve centers in Khartoum from 1 August 2012 to 31 July 2013. A standardized data collection form was used in 1015 patients. Factors were evaluated using Cox regression. The analyzed patients were (534; 52.6%) and the excluded patients were; (194; 19.1%) transferred to other centers, (165; 16.3%) died, (84; 8.3%) lost to follow-up and (38; 3.7%) underwent renal transplantation. Age of ‘45–64’ year [HR = 1.65, 95% CI (1.09–2.49)]; age ‘≥ 65’, HR = 2.30, (1.46–3.62); hyperlipidemia, HR = 2.10, (1.33–3.32); diabetes mellitus, HR = 1.43, (1.02–1.99) and ‘oral iron and vitamins’ HR = 2.30, (1.51–3.51) were factors increase mortality. Female, HR = 0.55, (0.37–0.82); smoking, HR = 0.53, (0.36–0.79), and pyelonephritis, HR = 0.22, (0.05–0.88) were inversely associated. Advanced age, hyperlipidemia, diabetes mellitus and ‘oral iron and vitamins’ were important factors significantly affecting mortality.