ABSTRACT
This chapter discusses different mechanisms of drug delivery in several clinical conditions in obstetrics and gynecology. It presents it on a time axis of a modern woman's lifetime. In early reproductive years, many women try to postpone childbirth; drugs and devices used for contraception are discussed. Barriers agents are one of the methods traditionally employed for this purpose. These agents represent a direct drug delivery mechanism, where the biomaterial is directly applied over the injured target tissue. Barriers may be either liquid or solid, and the latter can be absorbable or nonabsorbable. This barrier is composed of a combination of polyethylene oxide (PEO) and sodium carboxymethyl cellulose (CMC), which is stabilized with calcium and made isotonic through the use of sodium chloride. As oppose to the solid alternative, Intercoat is injected into the peritoneal cavity with a syringe that is provided with the product instead of being placed directly over the exposed area.
