ABSTRACT

Cervical tumors can be divided into several histological types such as squamous cell carcinoma, adenocarcinoma, mixed carcinomas, neuroendocrine carcinomas, and others. The cervix is the inferior portion of the uterus. Cervical cancer is the second most common cancer in women worldwide, with an estimation of 528,000 new cases per year and 266,000 deaths. Human papillomavirus (HPV) infection is considered necessary for development of the disease. Cervical cancer at the initial stages is usually an asymptomatic illness. When present, the most common symptoms are abnormal genital bleeding, postcoital bleeding, or malodorous discharge. The International Federation of Gynecology and Obstetrics (FIGO) classification is based on tumor size, vaginal or parametrial involvement, bladder or rectum extension, and distant metastasis. Depending on the stage, primary treatment consists of surgery, radiotherapy, or a combination of radiotherapy and chemotherapy. In the case of surgical contraindication, initial stages can be treated only with radiotherapy.